job description
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In our gut there are 300-500 different bacteria, more than 200 different viruses and an unknown number of fungi, which form a complex community, the gut microbiota. The gut microbiota plays a vital role in our health. However, there are many unknowns about how gene expression is regulated in these communities and how interactions between bacteria, viruses and fungi affect gene expression. Bacterial genomes are tightly organized within the bacterial cell, and DNA-binding proteins are shaping its three-dimensional structure. However, the effect of communities on the three-dimensional organization and coordination of gene expression is unknown. This project focuses on multi-omics analysis of the microbiome. The successful candidate will utilize advanced sequencing data and computational methods to reveal novel regulatory mechanisms of microbial communities, including gene expression and interactions with bacteriomes, fungal biomes, and viromes. The project will use state-of-the-art computational methods to analyze metagenomic, Hi-C and Hi-Pore-C sequencing data. The project aims to elucidate the correlations between metagenomes, metaglutellomes, and metaproteomes to deepen our understanding of how microbial communities are regulated. This interdisciplinary project offers the opportunity for groundbreaking discoveries in microbiome research and its impact on health and disease.
offer requirements
The strategic goal of the School of Mathematics and Natural Sciences is to be among the European leaders in research, education and innovation. Candidates for these scholarships will be selected in line with this objective and should be at the top of their class in terms of academic qualifications. Master’s degree (or equivalent) in Bioinformatics, Computational Biology, Microbiology or a related field. Proficiency in Python, C++ or R programming, statistical analysis and visualization. Excellent written and verbal communication skills in English. Desired qualifications: familiarity with genomics, metagenomics, or microbial ecology. Proficiency in UNIX/Linux and Bash/Shell scripting. Experience with reproducible data analysis, including workflow management systems such as Snakemake or Nextflow. Experience with multi-omics analysis. Experience analyzing high-throughput sequencing or Hi-C data. Interest in microbial community ecology (including fungal biota and viral population dynamics). Ability to collaborate across disciplines and contribute to scientific outreach. Proven organizational skills. Communication skills in Norwegian or Scandinavian. Candidates without a Master’s degree have until June 30, 2025 to complete the final exam. Language requirements: good oral and written communication skills in English. English language requirements and exemptions for applicants from countries outside the EU/EEA: https://www.mn.uio.no/english/research/phd/regulations/regulations.html#toc8成绩要求: The criteria are as follows In the Norwegian education system, the average of the Bachelor’s degree program In the Norwegian education system, the average grade for Bachelor’s degree programs must be C or better. Master’s degree programs must have a grade average of B or better in the Norwegian education system. The master’s thesis must have a grade of B or better in the Norwegian education system. The purpose of the fellowship is to conduct research training leading to successful completion of the doctoral degree. For more information, please visit: http://www.mn.uio.no/english/research/phd/Colourbox我们想从你身上看到什么? We are looking for candidates with the ability and motivation to work in an international, highly interdisciplinary team. Employment in this position is based on a comprehensive assessment of all qualification requirements applicable to the position, including personal qualifications.
offer benefits/salary
Exciting and meaningful work in an organization with an important social mission, contributing to knowledge development, education and enlightenment for sustainable, equitable and knowledge-based societies. Vibrant international academic environment Family-friendly environment in Oslo, rich cultural and outdoor opportunities Good benefits package Career development program Join the Norwegian National Pension Association (Statens Pensjonskasse), one of the best pension plans in Norway, offering favorable mortgages and a good insurance plan. The salary range for the position of PhD researcher (job code 1017) is NOK 536,200-575,400, depending on competence and experience. 2% is deducted from the salary as a statutory contribution to the National Pension Fund. For more information on the benefits of working in the public sector, please visit the Employer Portal.Inclusive working life and diversity at UiO Inclusion and diversity are an advantage. The goal of UiO’s personnel policy is to achieve a balanced gender composition. In addition, we expect employees to have different expertise, life experiences and perspectives. If there are qualified applicants with disabilities, employment gaps or immigrant backgrounds, we will invite at least one applicant from each category for an interview. We hope you will apply for the position. For more information about UiO’s Gender Equity Initiative, click here.